Men’s Health:
Tirzepatide + Tadalafil

Get All-In-One Help With Erectile Dysfunction & Weight Loss

Try our compounded medication containing two FDA-approved active ingredients, tirzepatide & tadalafil, that together support weight loss and more reliable erections.

Take control of your sexual health, plus lose stubborn pounds with our simple, fast-absorbing, under-your-tongue gel. Get help losing weight with tirzepatide, when combined with ED medication, has been proven to increase blood flow and make it easier to get and keep an erection.

Our compounded medication is easy to use, easy on the stomach, and as easy as brushing your teeth. Just place it under your tongue for five minutes after one of your daily routines. This innovative method may also support areas of men’s health often linked to weight, such as energy, confidence, and sexual wellness.

No claims are made regarding the safety or efficacy of our compounded formulations. they are prepared and dispensed solely in response to an unsolicited request by a licensed prescriber, or patient, as allowed under applicable compounding laws.

GetReliefRX's compounded sublingual Semaglutide + Tadalafil

Men’s Health:
Tirzepatide + Tadalafil

Try our compounded medication containing two FDA-approved active ingredients, tirzepatide & tadalafil, that together support weight loss and more reliable erections.

Take control of your sexual health, plus lose stubborn pounds with our simple, fast-absorbing, under-your-tongue gel. Get help losing weight with tirzepatide, when combined with ED medication, has been proven to increase blood flow and make it easier to get and keep an erection.

Our compounded medication is easy to use, easy on the stomach, and as easy as brushing your teeth. Just place it under your tongue for five minutes after one of your daily routines. This innovative method may also support areas of men’s health often linked to weight, such as energy, confidence, and sexual wellness.

No claims are made regarding the safety or efficacy of our compounded formulations. they are prepared and dispensed solely in response to an unsolicited request by a licensed prescriber, or patient, as allowed under applicable compounding laws.

GetReliefRX's compounded sublingual Semaglutide + Tadalafil

Weight Loss Is Known To Help These Symptoms & Conditions

How Does It Work?

No complicated steps—just a straightforward process designed to safely get you the right prescription quickly and conveniently.

Step 1

Fill out a HIPAA Compliant Medical Assessment

Step 2

Get Prescribed by a Licensed Medical Professional

Step 3

Receive your Medication, Delivered straight to your door
A man wearing a smock and gloves holding a prescription medication and a syringe.

What Is Sublingual Suspension?

Drop. Absorb. Repeat.

Our medication comes in a smooth, mint-flavored gel-drops. You place it beneath your tongue, hold for five minutes, and you’re done.

This under-the-tongue method works by delivering medication through the soft tissue in your mouth, bypassing your digestive system and skipping the need for needles or pills.

That’s why a clean mouth makes all the difference.

Brushing and flossing beforehand helps open up the gums, making absorption easier, faster, and more effective.

Your Support Team is ready to help!

Real Talk About Your Weight & Your Sex Life

Could I possibly improve my sex life by taking tirzepatide and tadalafil together?

Yes! While tadalafil is formulated to help men get and keep an erection with sexual stimulation, losing even a modest amount of weight can improve erectile dysfunction (ED), increase libido, and lead to greater stamina, contributing to a more satisfying sexual experience. With less fat, there’s less estrogen, and testosterone levels can rise, and blood flow is more likely to get to all the right places.

In fact, men who lose just 10 percent of their total body weight report significant improvements in their sexual quality of life (Duke Univ. 2005), so using tadalifil AND tirzepatide may improve both short-term and long-term sexual performance and satisfaction. Also, obesity increases the risk of ED by 30-90% compared to normal-weight men, and men with ED are more likely to be overweight or obese.

By addressing body confidence, health improvement, and sexual performance, men feel better inside and out – they’re losing weight, gaining energy, and improving intimacy all at the same time.

 

FAQ: Compounded Tirzepatide + Tadalafil
Sublingual Suspension

What does Tadalafil do to help with erectile dysfunction?

Tadalafil improves blood flow so it’s easier to get and keep an erection when you’re aroused. Typically, a chemical in the body makes blood vessels relax so more blood can get in to your penis, but sometimes another enzyme quickly shuts that process down. Tadalafil blocks that enzyme, making it easier to get and keep an erection with sexual stimulation.

Tirzepatide is a once-daily medication that supports weight loss by targeting the body’s natural hunger and fullness signals. It helps reduce appetite, curb cravings, and improve how your body uses insulin, making it easier to eat less and lose weight. Beyond weight management, tirzepatide has been shown to improve blood sugar control, support heart health, and boost overall energy levels. Many men begin noticing reduced appetite within the first couple of weeks, with steady weight loss and health benefits building over time.

The active ED ingredient (tadalafil) will gradually build up in your system, and once it’s reached an effective level (normally around 5-7 days after you start taking it), you may find that you are able to get an erection whenever you’re sexually stimulated. By taking the medication every day, the level of Tadalafil in your blood should remain steady, giving you continuous erection support when sexually stimulated.

Tirzepatide, the active weight loss ingredient, typically takes about 3-4 weeks to take full effect, but the timeline depends on the specific effect being measured. Appetite control, weight loss, and blood sugar improvements are all potential benefits of tirzepatide, and studies show the most meaningful results (substantial weight loss and metabolic improvement) usually occur over 3 to 6 months, especially once the dose is titrated to the higher ranges.  

Simply take it as soon as you remember. However, if it’s close to the time your next dose is due, skip the missed dose and just go straight on to the next. Don’t take two doses at the same time, as this could increase your risk of experiencing negative side effects.

The Science Behind...

Semaglutide (GLP-1's):

Semaglutide is a GLP-1 receptor agonist, meaning it mimics the activity of a naturally occurring gut hormone called glucagon-like peptide-1 (GLP-1). This hormone plays an important role in regulating appetite, insulin secretion, and glucose balance.

By activating GLP-1 receptors, semaglutide helps send signals to the brain that influence satiety and metabolic function. This targeted action supports improved blood sugar control and weight management.

Tirzepatide:

Tirzepatide is a dual GIP and GLP-1 receptor agonist, meaning it mimics the activity of two naturally occurring gut hormones: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). These hormones play important roles in regulating appetite, insulin secretion, and glucose balance.

 

By activating both GIP and GLP-1 receptors, tirzepatide helps send signals to the brain that influence satiety and metabolic function. This dual action is what sets it apart from GLP-1–only therapies.

Tadalafil:

Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor, meaning it blocks the activity of an enzyme that affects blood vessel relaxation and blood flow. This process plays an important role in supporting normal erectile function.

By enhancing blood flow in response to sexual stimulation, tadalafil supports improved erectile function. Its longer duration of action provides more flexibility compared to other treatments in the same class.

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